Breakpoints are part of a system for categorising microorganisms as susceptible (S and I) and resistant (R) to agents approved for use in the treatment of infectious diseases. Below are links to the yearly updated breakpoint tables, but other parts of the system are equally important. These are for example "Expert Rules" and "Expected Phenotypes", "What to do when there are no breakpoints" (and other guidance documents), how to cope with "IE", "Dash", "Breakpoints in brackets" and disease specific breakpoints. All major changes have been subjected to public consultation and following these will facilitate understanding the EUCAST process.

• Clinical breakpoints (v 14.0) - file for printing (1 Jan, 2024)
• Clinical breakpoints (v 14.0)  - file for screen (1 Jan, 2024)
• Aztreonam-avibactam - Addendum (22 May, 2024). Rationale Document available.
• Cefepime-enmetazobactam - Addendum (22 May, 2024). Rationale document available.
• Clinical breakpoints - fungi 
• Dosages (v 14.0) - file for printing and screen (1 Jan, 2024)

The major changes between the 2023 and 2024 breakpoint tables are:

• Fosfomycin iv breakpoints revised
• Cefiderocol ATUs revised, and zone diameter breakpoint for Enterobacterales adjusted
• Ciprofloxacin breakpoints for staphylococci revised
• Breakpoint for C. difficile and fidaxomicin added
• Breakpoints for Bacillus anthracis added
• Breakpoints for Brucella melitensis added
• PK-PD breakpoints removed from the table (see explanation in the PK-PD tab) and "When there are no breakpoints" 

For questions and comments on breakpoints, use the EUCAST subject related contact form.

Make sure the device you are using for the presentation of tables can correctly display footnotes (Note₁,Note²) and other typographical tools. 

• EUCAST instruction video on how to use the breakpoint table - download here.

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Breakpoints published in Addendum during the year will be part of the next Clinical breakpoint table. Older, no longer valid, breakpoint tables can be accessed through the archive. 

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Definitions of clinical breakpoints and epidemiological cut off values

Modified definitions valid from 1 January, 2019.